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In this state, the mitochondrial alterations described in acute ethanol conditions are also accompanied by a period of reduced activity of the electron respiratory chain complexes [69] and a loss of mitochondrial membrane potential [69] that suggests a major state of mitochondrial dysfunction (Figure 1.2)

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32 TRIM37 was considered to be associated with chemotherapy resistance and metastasis of TNBC in vitro and in vivo studies

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In the context of POTS and neuropathic dysautonomia, where blood vessels fail to constrict properly upon standing, improving endothelial health is crucial for maintaining adequate blood pressure and cerebral perfusion

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